全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM08715G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality XYLT1 antibody (N-term).
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分子量 |
107569 Da
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細胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Single-pass type II membrane protein Golgi apparatus membrane; Single- pass type II membrane protein. Secreted. Note=Some fraction is also found in the extracellular space together with chondroitin sulfate proteoglycans, suggesting that it can be secreted
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
126-155 aa
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靶點 |
This XYLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-155 amino acids from the N-terminal region of human XYLT1.
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亞型 |
Rabbit Ig
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通用名 |
XT1
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基因ID |
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UniProt ID |
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功能 |
Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes.
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總結(jié) |
This locus encodes a xylosyltransferase enzyme. Theencoded protein catalyzes transfer of UDP-xylose to serine residuesof an acceptor protein substrate. This transfer reaction isnecessary for biosynthesis of glycosaminoglycan chains. Mutationsin this gene have been associated with increased severity ofpseudoxanthoma elasticum.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, FC, E
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稀釋方法 |
WB~~1:1000
FC~~1:10~50
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別名 |
Xylosyltransferase 1, Peptide O-xylosyltransferase 1, Xylosyltransferase I, XT-I, XylT-I, XYLT1, XT1
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圖像 |
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說明書 |
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數(shù)量 |
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