品牌 |
Leading Biology |
貨號 |
APR14234G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality OTOA antibody (N-term).
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分子量 |
128533 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Apical cell membrane; Lipid- anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix. Note=At the interface between the apical surface of the epithelia and the overlying acellular gel of the tectorial and otoconial membranes.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Mouse
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免疫原 |
92-120 aa
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靶點 |
This OTOA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-120 amino acids from the N-terminal region of human OTOA.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
May act as an adhesion molecule.
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總結(jié) |
The protein encoded by this gene is specifically expressedin the inner ear, and is located at the interface between theapical surface of the inner ear sensory epithelia and theiroverlying acellular gels. It is prposed that this protein isinvolved in the attachment of the inner ear acellular gels to theapical surface of the underlying nonsensory cells. Mutations inthis gene are associated with autosomal recessive deafness type 22(DFNB22). Alternatively spliced transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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別名 |
Otoancorin, OTOA
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圖像 |
OTOA Antibody (N-term) (Cat. APR14234G) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the OTOA antibody detected the OTOA protein (arrow).
OTOA Antibody (N-term) (Cat. APR14234G)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OTOA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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說明書 |
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數(shù)量 |
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