品牌 |
Leading Biology | 貨號(hào) |
APR06925G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LANCL2 Antibody.
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分子量 |
Predicted: 50 kDa; Observed: 48 kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Cell membrane. Note=Localizes to the juxta-nuclear vesicles. Associates with the cortical actin cytoskeleton. Cholesterol depletion by methyl-beta- cyclodextrin causes partial dissociation from the cell membrane in vitro and an enhanced cell detachment from the matrix in vivo Membrane-association is important for the increased cellular sensitivity to an anticancer drug (adriamycin)
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
LANCL2; LANCL2 antibody is human, mouse and rat reactive.
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亞型 |
IgG
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通用名 |
GPR69B, TASP
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基因ID |
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UniProt ID |
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功能 |
Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes.
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總結(jié) |
LANCL2 (LanC-like protein 2), also known as TASP (testis-specific adriamycin sensitivity protein) or GPR69B, is a 450 amino acid member of the LanC-like protein family (1). It is expressed highly in brain and testis and localized to the nucleus, cytoplasm and cell membrane (2,3). LANCL2 is necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes (3,4).
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, E
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圖像 |
Western blot analysis of LANCL2 in human brain tissue lysate with LANCL2 antibody at 1 μg/ml. Immunohistochemistry of LANCL2 in mouse brain tissue with LANCL2 antibody at 5 μg/mL. |
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說明書 |
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數(shù)量 |
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