品牌 |
Leading Biology | 貨號 |
APR06834G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CEACAM5 Antibody .
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分子量 |
Predicted: 77 kDa Observed: 80kDa
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
CEACAM5; CEACAM5 antibody is human, mouse and rat reactive. CEACAM5 antibody is predicted to not cross-react with other CEACAM protein family members.
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亞型 |
IgG
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通用名 |
CEA
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基因ID |
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UniProt ID |
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功能 |
Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
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總結(jié) |
CEACAM5 is a member of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily (1,2). CEACAM proteins are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation (2). CEACAM5 has been shown to be overexpressed in a majority of carcinomas and has been suggested to be a intercellular adhesion molecule involved in cancer invasion and metastasis (3).
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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圖像 |
Western blot analysis of CEACAM5 in rat lung tissue lysate with CEACAM5 antibody at (A) 1 and (B) 2 μg/ml. Immunofluorescence of CEACAM5 in human lung tissue with CEACAM5 antibody at 20 μg/mL. |
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說明書 |
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數(shù)量 |
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