全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR06819G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GBP5 Antibody.
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分子量 |
Predicted: 64 kDa Observed: 66 kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Membrane; Lipid-anchor.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點 |
GBP5; GBP5 antibody is predicted to not cross-react with other GBP family members.
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亞型 |
IgG
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基因ID |
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UniProt ID |
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功能 |
Stimulates the NLRP3 inflammasome assembly upon bacterial challenge.
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總結(jié) |
GBP5 Antibody: The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN). GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble but not crystalline inflammasome priming agents.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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圖像 |
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說明書 |
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數(shù)量 |
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