品牌 |
Leading Biology | 貨號(hào) |
APR06810G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PRKCDBP Antibody.
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分子量 |
29 kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm {ECO:0000250|UniProtKB:Q91VJ2}.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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靶點(diǎn) |
PRKCDBP; It is predicted to not cross-react with other members of the cavin family.
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亞型 |
IgG
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通用名 |
SRBC
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基因ID |
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UniProt ID |
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功能 |
Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2. Seems to have an immune potentiation function.
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總結(jié) |
PRKCDBP Antibody: The protein kinase C delta (PKC-δ) binding protein (PRKCDBP), also known as cavin-3, is a member of the cavin family of proteins that are involved in caveolin formation and regulation. PRKCDBP was initially identified in a screen of cultured cell lines for proteins that were strongly induced by serum starvation. Studies indicate that PRKCDBP binds not only to PKC-δ but also to caveolin-1 and helps regulate caveolin traffic and function. Similar to other members of the cavin family, the expression of PRKCDBP was found to be down-regulated in various cancer cell lines, suggesting a possible tumor suppressor function of PRKCDBP.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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圖像 |
Western blot analysis of PRKCDBP in A20 cell lysate with PRKCDBP antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide. Immunohistochemistry of PRKCDBP in human spleen tissue with PRKCDBP antibody at 2.5 μg/ml. Immunofluorescence of PRKCDBP in human spleen tissue with PRKCDBP antibody at 20 μg/ml. |
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說明書 |
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數(shù)量 |
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