品牌 |
Leading Biology |
貨號 |
APR06806G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CCL17 Antibody.
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分子量 |
10 kDa
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細胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點 |
CCL17;
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亞型 |
IgG
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通用名 |
SCYA17, TARC
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基因ID |
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UniProt ID |
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功能 |
Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.
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總結(jié) |
CCL17 Antibody: CCL17, also known as TARC, binds to chemokine receptors CCR4 and CCR8 and plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. CCL17 is secreted from monocyte-derived DCs and endothelial cells and is responsible for selective recruitment and migration of activated Th2 lymphocytes. CCL17 is also required for CCR7 and CXCR4-dependent migration of cutaneous dendritic cells under inflammatory conditions.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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圖像 |
Western blot analysis of CCL17 in rat spleen tissue lysate with CCL17 antibody at (A) 1 and (B) 2 μg/mL
Immunohistochemistry of CCL17 in spleen tissue with CCL17 antibody at 5 μg/ml.
Immunofluorescence of CCL17 in human spleen tissue with CCL17 antibody at 20 μg/ml.
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說明書 |
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數(shù)量 |
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