品牌 |
Leading Biology | 貨號(hào) |
APR06791G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TSPY1S Antibody.
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分子量 |
32 kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Also found in nucleus
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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靶點(diǎn) |
TSPY1; TSPY1S antibody is human and mouse reactive. At least three isoforms of TSPY1 are known to exist; this antibody will detect only TSPY1S
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亞型 |
IgG
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通用名 |
TSPY
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基因ID |
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UniProt ID |
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功能 |
May be involved in sperm differentiation and proliferation.
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總結(jié) |
TSPY1S Antibody: Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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圖像 |
Western blot analysis of TSPY1S in A20 cell lysate with TSPY1S antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide. |
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說明書 |
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數(shù)量 |
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