品牌 |
Leading Biology | 貨號(hào) |
APR06755G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ESRRB Antibody.
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分子量 |
56208 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407, ECO:0000269|PubMed:18775884}
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
ESRRB;
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亞型 |
IgG
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通用名 |
ERRB2, ESRL2, NR3B2
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基因ID |
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UniProt ID |
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功能 |
Nuclear receptor, may regulate ESR1 transcriptional activity. Induces the expression of PERM1 in the skeletal muscle.
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總結(jié) |
ESRRB Antibody: The estrogen-related receptor beta (ESRRB) was initially identified in mouse embryonic carcinoma stem cells and was found to be expressed exclusively in trophoblast progenitor cells between days 6.5 and 7.5 post coitum. Recent studies have shown that ESRRB is part of an POU5F1/Oct4-centered protein interaction network in embryonic stem (ES) cells. It is thought to interact with other ES transcription factors such as NANOG within this network, activating POU5F1 transcription and thereby sustaining self-renewal and pluripotency in ES cells.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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圖像 |
Western blot analysis of ESRRB in human heart tissue lysate with ESRRB antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide. Immunohistochemistry of ESRR8 in human heart tissue with ESRR8 antibody at 5 μg/mL. Immunofluorescence of ESRRB in human heart tissue with ESRRB antibody at 20 μg/mL. |
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說明書 |
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數(shù)量 |
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