全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APR06742G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MLIP Antibody.
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分子量 |
50429 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus. Nucleus envelope. Nucleus, PML body
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
MLIP; At least three isoforms of MLIP are known to exist.
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亞型 |
IgG
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通用名 |
C6orf142
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基因ID |
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UniProt ID |
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總結(jié) |
MLIP Antibody: The muscle-enriched A-type lamin-interacting protein (MLIP) is ubiquitously expressed, although most predominantly in heart, skeletal and smooth muscle, and interacts directly and co-localizes with lamin A and C in the nuclear envelope. MLIP also co-localizes with promyelocytic leukemia (PML) bodies within the nucleus. Decreasing lamin A/C expression with siRNA results in the upregulation and mislocalization of MLIP, suggesting that MLIP localization to the nuclear envelope is dependent on the lamin proteins. It has been suggested that MLIP may function as a tethering protein linking LMNA to factors within the nuclear envelope of within PML bodies
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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圖像 |
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說明書 |
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數(shù)量 |
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