全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR06736G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Thymopoietin Antibody.
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分子量 |
75492 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus. Chromosome. Note=Expressed diffusely throughout the nucleus
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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靶點(diǎn) |
TMPO; At least three isoforms of Thymopoietin are known to exist; this antibody will detect all isoforms. Thymopoietin antibody is predicted to not cross-react with other LEM domain-containing proteins.
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亞型 |
IgG
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通用名 |
LAP2
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基因ID |
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UniProt ID |
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功能 |
May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. Plays an important role, together with LMNA, in the nuclear anchorage of RB1.
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總結(jié) |
Thymopoietin Antibody: Thymopoietin (TMPO), also known as LAP2, is a widely expressed lem-domain-containing nuclear protein that is thought to play an important role in the regulation of nuclear architecture by binding lamin B1 and chromosomes in a manner regulated by phosphorylation during mitosis. Thymopoietin associates with nucleoplasmic lamins A/C, which are encoded by the dilated cardiomyopathy (DCM) gene LMNA; mutations in Thymopoietin disrupt this binding, suggesting that Thymopoietin may be a candidate disease gene for DCM.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IF, ICC, E
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圖像 |
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說明書 |
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數(shù)量 |
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