品牌 |
Leading Biology | 貨號 |
APR06732G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PRICKLE4 Antibody.
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分子量 |
37551 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點 |
PRICKLE4; Two isoforms of PRICKLE4 are known to exist. PRICKLE4 antibody is predicted to not cross-react with other PRICKLE protein family members.
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亞型 |
IgG
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通用名 |
C6orf49, OEBT
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基因ID |
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UniProt ID |
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總結(jié) |
PRICKLE4 Antibody: PRICKLE4, also known as over-expressed breast tumor protein (OBTP), is a member of the LIM family of proteins. It possesses two LIM domains as well as a PET domain and is thought to localize to the nucleus. Its expression in multiple malignant tissue differentiations indicate that it may play a role in cancer differentiation. Two other members of the LIM family, PRICKLE1 and PRICKLE2, are thought to function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity, suggesting the PRICKLE4 may play a similar role.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IF, ICC, E
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圖像 |
Western blot analysis of PRICKLE4 in A549 cell lysate with PRICKLE4 antibody at 0.25 μg/ml in the (A) absence and (B) presence of blocking peptide. Immunocytochemistry of PRICKLE4 in A549 cells with PRICKLE4 antibody at 5 μg/mL. Immunofluorescence of PRICKL4 in A549 cells with PRICKLE4 antibody at 20 μg/mL. |
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說明書 |
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數(shù)量 |
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