品牌 |
Leading Biology | 貨號(hào) |
APR06714G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TMEM204 Antibody.
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分子量 |
24540 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell junction, adherens junction. Cell membrane; Multi-pass membrane protein. Note=Colocalizes with the beta- catenin adherins
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
TMEM204; At least two isoforms of TMEM204 are known to exist; this antibody will recognize both isoforms.
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亞型 |
IgG
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通用名 |
C16orf30, CLP24
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基因ID |
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UniProt ID |
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功能 |
Can influence paracellular permeability. Appears to be involved in cell-cell interactions through adherens.
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總結(jié) |
TMEM204 Antibody: Transmembrane protein 204 (TMEM204) is a four-transmembrane protein that is induced under hypoxic conditions. It localizes to cell-cell junctions and co-localizes with the beta-catenin adherens junction-associated protein, but not with tight junctions. Overexpression of TMEM204 results in decreased adhesion between cells, indicating that TMEM204 is an adherens junction protein that modulates cell adhesion and potentially angiogenesis. Recent evidence suggests TMEM204 may also be involved in epilepsy.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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圖像 |
Western blot analysis of TMEM204 in human brain tissue lysate with TMEM204 antibody at 1 μg/mL . Immunohistochemistry of TMEM204 in mouse brain tissue with TMEM204 antibody at 5 μg/mL. Immunofluorescence of TMEM204 in mouse brain tissue with TMEM204 antibody at 20 μg/mL. |
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說(shuō)明書 |
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數(shù)量 |
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