品牌 |
Leading Biology | 貨號 |
APR06679G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PLAC1 Antibody.
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分子量 |
23616 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點 |
PLAC1;
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亞型 |
IgG
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基因ID |
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UniProt ID |
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功能 |
May play a role in placental development.
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總結(jié) |
PLAC1 Antibody: PLAC1 was initially identified as a protein expressed specifically in the placenta and other cells derived from the trophoblast lineage during embryonic development, but has also been found to be expressed ectopically in a wide range of human malignancies, particularly breast cancers. PLAC1 is a membrane-associated protein that is thought to serve a receptor-like function modulating cell-cell or ligand receptor interactions unique to the maternal-placental interface. Decreased expression of PLAC1 is associated with decreased expression of cyclin D1 and reduced expression of AKT kinase, which, combined with the fact that PLAC1 is expressed on the surface of cancer cells, suggests that PLAC1 may be an effective candidate for immunotherapeutic treatments of cancer.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IF, ICC, E
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圖像 |
Western blot analysis of PLAC1 in human placenta tissue lysate with PLAC1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide. Immunocytochemistry of PLAC1 in HeLa cells with PLAC1 antibody at 10 μg/mL. Immunofluorescence of PLAC1 in Hela cells with PLAC1 antibody at 20 μg/mL. |
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說明書 |
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數(shù)量 |
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