品牌 |
Leading Biology | 貨號 |
APR06670G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NALP8 Antibody.
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分子量 |
119430 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Rabbit
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種屬反應性 |
Human
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靶點 |
NLRP8;
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亞型 |
IgG
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通用名 |
NALP8, NOD16, PAN4
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基因ID |
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UniProt ID |
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功能 |
Involved in inflammation.
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總結(jié) |
NALP8 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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圖像 |
Western blot analysis of NALP8 in human colon tissue lysate with NALP8 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide. |
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說明書 |
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數(shù)量 |
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