品牌 |
Leading Biology | 貨號 |
APR06564G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality JMJD5 Antibody.
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分子量 |
47270 Da
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細胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點 |
JMJD5;
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亞型 |
IgG
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通用名 |
JMJD5
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基因ID |
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UniProt ID |
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功能 |
Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.
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總結(jié) |
JMJD5 Antibody: The jumonji domain-containing protein (JMJD) family is defined by the presence of the JmjC domain that is observed in several diverse species. While several JMJD proteins have been identified as being involved in chromatin regulation, histone demethylation and development, the function of JMJD5 has not been identified. JMJD5 is expressed in multiple tissues.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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圖像 |
Western blot analysis of JMJD5 in human liver tissue lysate with JMJD5 antibody at (A) 1 and (B) 2 μg/mL. Immunohistochemistry of JMJD5 in rat liver tissue with JMJD5 antibody at 2.5 μg/mL. Immunofluorescence of JMJD5 in Rat Liver cells with JMJD5 antibody at 20 μg/mL. |
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說明書 |
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數(shù)量 |
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