品牌 |
Leading Biology | 貨號 |
APR06528G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MTCH2 Antibody.
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分子量 |
33499 Da
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細胞定位 |
Antigen Cellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse
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靶點 |
Mtch2;
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亞型 |
IgG
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基因ID |
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UniProt ID |
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功能 |
The substrate transported is not yet known. Induces mitochondrial depolarization (By similarity).
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總結 |
MTCH2 Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, IF, E
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圖像 |
Western blot analysis of MTCH2 in 293 cell lysate with MTCH2 antibody at 1 μg/mL. Immunohistochemistry of MTCH2 in mouse kidney tissue with MTCH2 antibody at 5 μg/mL. Immunofluorescence of MTCH2 in Mouse Kidney cells with MTCH2 antibody at 20 μg/mL. |
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說明書 |
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數(shù)量 |
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