FGF4 Antibody

APR06475G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR06475G		0.1 mg / ￥6950

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安諾倫（北京）生物科技有限公司

Tel: 400-965-8633
Tel: 010-56256916
Inquiry@annoron.com

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FGF4 Antibody

品牌	Leading Biology	貨號(hào)	APR06475G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FGF4 Antibody.
分子量	22048 Da
細(xì)胞定位	Antigen Cellular Localization: Secreted.
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
靶點(diǎn)	FGF4;
亞型	IgG
通用名	HST, HSTF1, KS3
基因ID	2249
UniProt ID	P08620
功能	Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal limb and cardiac valve development during embryogenesis.
總結(jié)	FGF4 Antibody: Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IF, ICC, E
圖像	Western blot analysis of FGF4 in NIH 3T3 cell lysate with FGF4 antibody at (A) 0.5 and (B) 1 μg/mL. Immunocytochemistry of FGF4 in 3T3 cells with FGF4 antibody at 2.5 μg/mL. Immunofluorescence of FGF4 in 3T3 cells with FGF4 antibody at 2.5 μg/mL.
說(shuō)明書(shū)	Product Datasheet Protocol
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