品牌 |
Leading Biology | 貨號(hào) |
APR06457G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality STEAP2 Antibody.
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分子量 |
Predicted: 54 kDa Observed: 55 kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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靶點(diǎn) |
STEAP2; This STEAP2 antibody does not cross-react with other STEAP proteins.
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亞型 |
IgG
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通用名 |
PCANAP1, STAMP1
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基因ID |
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UniProt ID |
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功能 |
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).
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總結(jié) |
STEAP2 Antibody: The six-transmembrane epithelial antigen of prostate 2 (STEAP2) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 3 and STEAP4), STEAP2 promotes both iron and copper reduction. STEAP2 expression in transfected cells also correlated with iron or copper uptake, suggesting that the STEAP family of proteins may function to stimulate iron and copper uptake. STEAP2 is widely expressed in many tissues in the plasma membrane, but is most highly expressed in prostate. At least three isoforms of STEAP2 are known to exist.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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圖像 |
Western blot analysis of STEAP2 in human prostate tissue lysate with STEAP2 antibody at 1 μg/mL. Immunohistochemistry of STEAP2 in human colon tissue with STEAP2 antibody at 2.5 μg/mL. Immunofluorescence of STEAP2 in Human Colon cells with STEAP2 antibody at 20 μg/mL. |
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說(shuō)明書 |
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數(shù)量 |
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