全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR06398G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Hrk Antibody.
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分子量 |
Predicted: 10 kDa Observed: 12 kDa
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細胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass membrane protein. Mitochondrion
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse
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靶點 |
HRK;
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亞型 |
IgG
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通用名 |
BID3
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基因ID |
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UniProt ID |
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功能 |
Promotes apoptosis.
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總結(jié) |
Hrk Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Hrk, a pro-apoptotic member of the Bcl-2 homology domain-3 (BH3)-only group of the Bcl-2 family of proteins, was also identified as novel protein induced during programmed neuronal death. It lacks significant homology to other Bcl-2 family members except for an 8-amino acid region that is similar to the BH3 motif of Bik. Hrk regulates apoptosis through interaction with the anti-apoptotic proteins Bcl-2 and Bcl-XL via this domain. It does not interact with the pro-apoptotic proteins Bax, Bak, or Bcl-XS. Hrk localizes to mitochondrial membranes in a pattern similar to that previously reported for Bcl-2 and Bcl-XL.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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圖像 |
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說明書 |
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數(shù)量 |
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