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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > NSMCE4A Antibody - C-terminal region品牌 |
Leading Biology | 貨號(hào) |
APR01814G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NSMCE4A Antibody - C-terminal region.
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分子量 |
44kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus. Chromosome, telomere
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
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通用名 |
C10orf86
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基因ID |
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UniProt ID |
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功能 |
Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies (APBs). Is involved in positive regulation of response to DNA damage stimulus.
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總結(jié) |
Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies (APBs). Is involved in positive regulation of response to DNA damage stimulus.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IF
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圖像 |
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說(shuō)明書 |
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數(shù)量 |
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