全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR01698G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RRP8 Antibody - N-terminal region.
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分子量 |
50kDa
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細胞定位 |
Antigen Cellular Localization:
Nucleus, nucleolus. Note=Localizes at rDNA locus
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宿主 |
Rabbit
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種屬反應性 |
Human, Rat, Rabbit, Horse, Yeast, Bovine, Guinea Pig, Dog
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通用名 |
KIAA0409, NML
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基因ID |
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UniProt ID |
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功能 |
Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys- 9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB
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圖像 |
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說明書 |
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數(shù)量 |
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| 選擇 | 品牌 | 貨號 | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領域 | 說明書 | 數(shù)量 | 目錄價 | |
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| 5 | Leading Biology | APR11512G | Bestrophin-1 (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
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