品牌 |
Leading Biology |
貨號 |
APR01452G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Casp3 Antibody - middle region.
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分子量 |
31kDa
|
細胞定位 |
Antigen Cellular Localization:
Cytoplasm.
|
宿主 |
Rabbit
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種屬反應性 |
Human, Rat, Pig, Goat, Sheep, Horse, Bovine, Guinea Pig, Dog
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通用名 |
Cpp32
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基因ID |
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UniProt ID |
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功能 |
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop- helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB
|
圖像 |
Host: Rabbit
Target Name: Casp3
Sample Tissue: Mouse Liver lysates
Antibody Dilution: 1.0μg/ml
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說明書 |
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數(shù)量 |
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