Ppargc1a antibody - middle region

APR00772G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR00772G		50 μg / ￥5450

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Ppargc1a antibody - middle region

品牌	Leading Biology	貨號(hào)	APR00772G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Ppargc1a antibody - middle region.
分子量	90kDa
細(xì)胞定位	Antigen Cellular Localization: Nucleus. Nucleus, PML body.
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat, Rabbit, Pig, Goat, Sheep, Horse, Bovine, Dog
通用名	Pgc1, Pgc1a, Ppargc1
基因ID	19017
UniProt ID	O70343
功能	Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner. Also involved in the integration of the circadian rhythms and energy metabolism. Required for oscillatory expression of clock genes, such as ARNTL/BMAL1 and NR1D1, through the coactivation of RORA and RORC, and metabolic genes, such as PDK4 and PEPCK. Isoform 4 specifically activates the expression of IGF1 and suppresses myostatin expression in skeletal muscle leading to muscle fiber hypertrophy.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB
圖像	Ppargc1a antibody - middle region (APR00772G) validated by WB using Transfected Melanoma Cell at 1:1000. Host: Rabbit Target Name:Ppargc1a Sample Tissue:SP2/0 Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration:1μg/ml Peptide Concentration: 5μg/ml Lysate Quantity: 25ug/lane Gel Concentration: 0.12% WB Suggested Anti-Ppargc1a Antibody Titration: 0.2-1 μg/ml ELISA Titer: 1:312500 Positive Control: SP2/0 cell lysate
說(shuō)明書(shū)	Product Datasheet Protocol
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