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全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APR00682G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Acd antibody - C-terminal region.
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分子量 |
45 KDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus. Chromosome, telomere
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat, Horse, Bovine, Dog
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基因ID |
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UniProt ID |
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功能 |
Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by increasing telomerase processivity (By similarity). Plays a role in shelterin complex assembly. May play an essential role in organogenesis of the developing embryo.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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圖像 |
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說(shuō)明書(shū) |
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數(shù)量 |
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