品牌 |
Leading Biology | 貨號(hào) |
APR00632G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TEAD4 antibody - middle region.
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分子量 |
44kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat, Pig, Horse, Bovine, Dog
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通用名 |
RTEF1, TCF13L1, TEF3
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基因ID |
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UniProt ID |
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功能 |
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IF
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圖像 |
WB Suggested Anti-TEAD4 Antibody Titration: .2-1 μg/mlELISA Titer: 1:125Positive Control: Transfected 293T Sample Type : HeLa<b>Primary Antibody Dilution: 4 μg/ml <b>Secondary Antibody : Anti-rabbit Alexa 546 <b>Secondary Antibody Dilution: 2 μg/ml <b>Gene Name : TEAD4 |
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說明書 |
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數(shù)量 |
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