品牌 |
Leading Biology | 貨號(hào) |
APR00557G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PSMD4 antibody - C-terminal region.
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分子量 |
41 kDa
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Sheep, Bovine
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靶點(diǎn) |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD4 encodes one of the non-ATPase subunits of the 19S regulator lid.
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通用名 |
MCB1
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基因ID |
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UniProt ID |
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功能 |
Binds and presumably selects ubiquitin-conjugates for destruction. Displays selectivity for longer polyubiquitin chains. Modulates intestinal fluid secretion.
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總結(jié) |
This is a rabbit polyclonal antibody against PSMD4. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC
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圖像 |
Human BrainRabbit Anti-PSMD4 Antibody Paraffin Embedded Tissue: Human neural cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 μg/ml Magnification: 400X PSMD4 antibody - C-terminal region (APR00557G) in Human Raji cells using Western BlotWB Suggested Anti-PSMD4 Antibody Titration: 0.2-1 μg/ml Positive Control: Raji cell lysatePSMD4 is strongly supported by BioGPS gene expression data to be expressed in Human Raji cells |
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說明書 |
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數(shù)量 |
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