品牌 |
Leading Biology |
貨號(hào) |
APR00011G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies |
研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PBR Antibody.
|
分子量 |
27399 Da
|
細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus.
|
宿主 |
Rabbit
|
種屬反應(yīng)性 |
Human, Mouse, Rat
|
靶點(diǎn) |
PBR
|
亞型 |
Rabbit IgG
|
通用名 |
FGF12B, FHF1
|
基因ID |
|
UniProt ID |
|
功能 |
Probably involved in nervous system development and function.
|
總結(jié) |
PBR (Peripheral-type Benzodiazepine Receptor) is a ubiquitous protein (18 kDa) found in most steroidogenic tissues. It is located primarily in the outer mitochondrial membrane of steroid-producing tissues and is found in association with a 34 kDa voltage-dependent anion channel protein (VDAC). PBR is involved in the regulation of cholesterol transport from the outer to the inner mitochondrial membrane. It is tho μght to be part of the mitochondrial permeability transition pore (PT) and to be involved in apoptosis.
|
形式 |
Liquid
|
儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
應(yīng)用 |
WB, IHC
|
圖像 |
Western blot analysis of PBR expression using: Lane 1: Jurkat cell lysate; Lane 2: Recombinant PBR; Lane 3: Rat kidney tissue lysate
|
說(shuō)明書(shū) |
|
數(shù)量 |
|