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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > ICOS Antibody

ICOS Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR03338G 50 μl / ¥4950

ICOS Antibody

品牌

Leading Biology

貨號(hào)

APR03338G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ICOS Antibody.

分子量

22625 Da

細(xì)胞定位

Antigen Cellular Localization: Isoform 1: Cell membrane; Single-pass type I membrane protein

宿主

Rabbit

種屬反應(yīng)性

Human, Mouse, Rat

靶點(diǎn)

Human ICOS

亞型

IgG

通用名

AILIM

基因ID

UniProt ID

功能

Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up- regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up- regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre- activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).

總結(jié)

Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up- regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up- regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre- activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, IF

稀釋方法

IF (1:50 - 1:200), IHC-P (5 μg/ml), WB (1:500 - 1:2000),

圖像

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunofluorescence analysis of MCF7 cell using ICOS antibody. Blue: DAPI for nuclear staining.

說(shuō)明書(shū)

數(shù)量

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