品牌 |
Leading Biology | 貨號(hào) |
APR03292G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MAPK4 / ERK4 Antibody (aa1-326).
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分子量 |
65922 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Translocates to the cytoplasm following interaction with MAPKAPK5.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
Human MAPK4 / ERK4
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亞型 |
IgG
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通用名 |
ERK4, PRKM4
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基因ID |
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UniProt ID |
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功能 |
Atypical MAPK protein. Phosphorylates microtubule- associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity).
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總結(jié) |
Atypical MAPK protein. Phosphorylates microtubule- associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity).
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, ICC
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稀釋方法 |
ICC (1:100 - 1:1000), IHC-P (7.5 μg/ml), WB (1:500 - 1:3000),
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圖像 |
Anti-MAPK4 / ERK4 antibody IHC staining of human small intestine. Immunofluorescence of paraformaldehyde-fixed HeLa using MAPK4 antibody at 1:200 dilution. Sample (30 ug whole cell lysate). A: H1299. 7.5% SDS PAGE. MAPK4 / ERK4 antibody diluted at 1:1000 |
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說(shuō)明書(shū) |
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數(shù)量 |
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