IL36RN / IL1F5 Antibody (C-Terminus)

APR03277G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR03277G		50 μg / ￥4950

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安諾倫（北京）生物科技有限公司

Tel: 400-965-8633
Tel: 010-56256916
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IL36RN / IL1F5 Antibody (C-Terminus)

品牌	Leading Biology	貨號(hào)	APR03277G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL36RN / IL1F5 Antibody (C-Terminus).
分子量	16962 Da
細(xì)胞定位	Antigen Cellular Localization: Secreted.
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
靶點(diǎn)	IL-36RN antibody is human specific. At least two isoforms of IL-36RN are known to exist.
亞型	IgG
通用名	FIL1D, IL1F5, IL1HY1, IL1L1, IL1RP3
基因ID	26525
UniProt ID	Q9UBH0
功能	Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.
總結(jié)	Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF, E
稀釋方法	IF (20 μg/ml), IHC-P (10 μg/ml), WB (1 - 2 μg/ml),
圖像	Anti-IL36RN / IL1F5 antibody IHC staining of human colon. Immunofluorescence of IL-36RN in rat small intestine tissue with IL-36RN antibody at 20 ug/ml. Western blot analysis of IL-36RN in 3T3 cell lysate with IL-36RN antibody at 1 ug/ml in (A) the...
說明書	Product Datasheet Protocol
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