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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > VWF / Von Willebrand Factor Antibody (FITC)品牌 |
Leading Biology | 貨號 |
APS00015G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality VWF / Von Willebrand Factor Antibody (FITC).
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分子量 |
309265 Da
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細胞定位 |
Antigen Cellular Localization:
Secreted. Secreted, extracellular space, extracellular matrix. Note=Localized to storage granules
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宿主 |
Sheep
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種屬反應(yīng)性 |
Human
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靶點 |
Human von Willebrand factor, a glycoprotein synthesized in endothelial cells and megakaryocytes which circulates in the blood associated with factor VIII in a non-covalent complex
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亞型 |
IgG
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通用名 |
F8VWF
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基因ID |
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UniProt ID |
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功能 |
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
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總結(jié) |
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC-P, IHC-Fr
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稀釋方法 |
IHC-Fr (1:50 - 1:100), IHC-P (1:100),
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圖像 |
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說明書 |
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數(shù)量 |
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