品牌 |
Leading Biology | 貨號 |
APR03185G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CD55 Antibody (aa71-330).
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分子量 |
41kDa
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細胞定位 |
Antigen Cellular Localization:
Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Secreted Isoform 5: Secreted Isoform 7: Cell membrane; Lipid-anchor, GPI-anchor
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宿主 |
Rabbit
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種屬反應性 |
Human
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靶點 |
Human CD55
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通用名 |
CR, DAF
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基因ID |
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UniProt ID |
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功能 |
This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.
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總結 |
This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, ICC
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稀釋方法 |
ICC (1:100-1:1000), IHC-P (5 μg/ml), WB (1:500-1:3000)
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圖像 |
Immunofluorescence of methanol-fixed HeLa using CD55 antibody at 1:200 dilution. Sample (30 ug of whole cell lysate). A: THP-1. 10% SDS PAGE. CD55 antibody diluted at 1:1000. Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE) |
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說明書 |
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數(shù)量 |
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5 | Leading Biology | APR11512G | Bestrophin-1 (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
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6 | Leading Biology | APG01407G | A3 Adenosine Receptor Antibody | 50 μl | Polyclonal Antibodies |
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