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當(dāng)前位置：首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > IL37 Antibody (N-Terminus)

IL37 Antibody (N-Terminus)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR03137G 50 μg / ￥4950

IL37 Antibody (N-Terminus)

品牌

 Leading Biology

貨號(hào)

 APR03137G

產(chǎn)品分類

 Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL37 Antibody (N-Terminus).

分子量
24kDa

細(xì)胞定位
Antigen Cellular Localization: Cytoplasm, cytosol. Nucleus. Secreted. Note=Stimulation with IL1B leads to colocalization with SMAD3 mostly in perinuclear regions. Only the CASP1-cleaved mature form translocates into the nucleus upon LPS stimulation

宿主
Rabbit

種屬反應(yīng)性
Human

靶點(diǎn)
IL-37 antibody is human specific. Multiple isoforms of IL-37 are known to exist; this antibody will only detect the largest isoform. IL-37 antibody is predicted to not cross-react with IL-36.

通用名
FIL1Z, IL1F7, IL1H4, IL1RP1

基因ID

UniProt ID

功能
Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation.

總結(jié)
Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation.

儲(chǔ)存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用
WB, IHC-P, IF, E

稀釋方法
IF (20 μg/ml), IHC-P (10 μg/ml), WB (1 μg/ml)

圖像

Western blot analysis of IL-37 in human lung tissue lysate with IL-37 antibody at 1 ug/ml in (A)...

Immunofluorescence of IL-12A in human kidney tissue with IL-12A antibody at 20 ug/ml.

說(shuō)明書(shū)

數(shù)量

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