品牌 |
Leading Biology |
貨號 |
APR02992G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PBK / TOPK Antibody (aa1-50).
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分子量 |
36kDa
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點 |
PBK/TOPK (Ab-9) Antibody detects endogenous levels of total PBK/TOPK protein.
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通用名 |
TOPK
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基因ID |
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UniProt ID |
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功能 |
Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.
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總結(jié) |
Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
ELISA (1:1000), IHC-P (5 μg/ml), WB (1:500-1:1000)
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圖像 |
Western blot of extracts from COS7 cells, treated with Nocodazole 1 ug/ml 16h, using PBK/TOPK...
Anti-PBK / TOPK antibody IHC of human thymus.
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說明書 |
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數(shù)量 |
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