全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APG01177G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PTPN6 / SHP1 Antibody (Internal).
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分子量 |
68kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=In neurons, translocates into the nucleus after treatment with angiotensin II (By similarity). Shuttles between the cytoplasm and nucleus via its association with PDPK1.
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宿主 |
Goat
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種屬反應(yīng)性 |
Human, Mouse, Rat, Hamster
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靶點(diǎn) |
Mouse PTPN6. This antibody is expected to recognise both reported isoforms (NP_536858.1and NP_002822.2).
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通用名 |
HCP, PTP1C
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基因ID |
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UniProt ID |
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功能 |
Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
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總結(jié) |
Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
ELISA (1:128000), IHC-P (5 μg/ml), WB (0.1-0.3 μg/ml)
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圖像 |
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說(shuō)明書 |
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數(shù)量 |
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