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當(dāng)前位置：首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Vitamin D Receptor / VDR Antibody (aa181-230)

Vitamin D Receptor / VDR Antibody (aa181-230)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR02904G 50 μl / ￥4950

Vitamin D Receptor / VDR Antibody (aa181-230)

品牌

 Leading Biology

貨號(hào)

 APR02904G

產(chǎn)品分類

 Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Vitamin D Receptor / VDR Antibody (aa181-230).

分子量
48kDa

細(xì)胞定位
Antigen Cellular Localization: Nucleus.

宿主
Rabbit

種屬反應(yīng)性
Human

靶點(diǎn)
Vitamin D Receptor (Ab-208) Antibody detects endogenous levels of total Vitamin D Receptor protein.

通用名
NR1I1

基因ID

UniProt ID

功能
Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.

總結(jié)
Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.

儲(chǔ)存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用
WB, IHC-P, IF, E

稀釋方法
ELISA (1:10000), IF (1:100-1:500), IHC-P (5 μg/ml), WB (1:500-1:1000) ,

圖像

Immunofluorescence of HeLa cells, using Vitamin D Receptor (Ab-208) Antibody.

Western blot of extracts from MCF-7 cells, using Vitamin D Receptor (Ab-208) Antibody.

Anti-VDR antibody IHC of human skin.

說(shuō)明書(shū)

數(shù)量

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