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當(dāng)前位置：首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > IRF4 Antibody (C-Terminus)

IRF4 Antibody (C-Terminus)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR02881G 50 μg / ￥4950

IRF4 Antibody (C-Terminus)

品牌

 Leading Biology

貨號(hào)

 APR02881G

產(chǎn)品分類

 Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IRF4 Antibody (C-Terminus).

分子量
52kDa

細(xì)胞定位
Antigen Cellular Localization: Nucleus.

宿主
Rabbit

種屬反應(yīng)性
Human

靶點(diǎn)
Human IRF4. IRF4 antibody is predicted to not cross-react with other IRF protein family members. IRF4 often migrates at a higher than predicted molecular weight in SDS-PAGE.

通用名
MUM1

基因ID

UniProt ID

功能
Transcriptional activator. Binds to the interferon- stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity).

總結(jié)
Transcriptional activator. Binds to the interferon- stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity).

儲(chǔ)存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用
WB, IHC-P, IF, ICC

稀釋方法
IHC-P (5 μg/ml), WB (1-2 μg/ml),

圖像

Immunocytochemistry of IRF4 in Jurkat cells with IRF4 antibody at 10 ug/ml.

Immunofluorescence of IRF4 in Jurkat cells with IRF4 antibody at 20 ug/ml.

說明書

數(shù)量

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