品牌 |
Leading Biology | 貨號 |
APR02860G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PEA15 / PEA-15 Antibody (aa81-130).
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分子量 |
15kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Note=Associated with microtubules
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
PEA-15 antibody detects endogenous levels of total PEA-15 protein.
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基因ID |
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UniProt ID |
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功能 |
Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.
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總結(jié) |
Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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稀釋方法 |
ELISA (1:40000), IF (1:100-1:500), IHC-P (10 μg/ml), WB (1:500-1:1000) ,
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圖像 |
Immunofluorescence of HeLa cells, using PEA-15 antibody. Western blot of extracts from Jurkat cells, treated with PMA 125 ng/ml 30, using PEA-15 antibody. Anti-PEA15 antibody IHC of human kidney, tubules. |
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說明書 |
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數(shù)量 |
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