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全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APG01154G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NUP50 Antibody (C-Terminus).
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分子量 |
50kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Localizes to the nucleoplasmic fibrils of the nuclear pore complex (By similarity). Dissociates from the NPC structure early during prophase of mitosis. Associates to the newly formed nuclear membrane during telophase.
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宿主 |
Goat
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種屬反應(yīng)性 |
Human, Mouse, Bovine
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靶點(diǎn) |
Human NUP50. This antibody is expected to recognise both reported isoforms (NP_009103.2; NP_705931.1).
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通用名 |
NPAP60L
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基因ID |
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UniProt ID |
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功能 |
Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin- alpha:beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
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總結(jié) |
Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin- alpha:beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
IHC-P (2.5-3.75 μg/ml), WB (0.2-1 μg/ml),
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圖像 |
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說(shuō)明書 |
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數(shù)量 |
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