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Polyclonal Antibodies >
NANOS3 / NOS-3 Antibody (C-Terminus)品牌 |
Leading Biology | 貨號(hào) |
APR02695G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NANOS3 / NOS-3 Antibody (C-Terminus).
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分子量 |
19kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Cytoplasmic granule. Cytoplasm, P-body. Note=The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Colocalizes with PUM2, EIF2S1 and TIAL1 in the stress granules. Colocalizes with DCP1A in the P-body (By similarity).
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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通用名 |
NOS3
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基因ID |
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UniProt ID |
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功能 |
Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax- dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.
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總結(jié) |
Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax- dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF
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稀釋方法 |
IHC-P (5 μg/ml), WB (1-2 μg/ml),
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圖像 |
Western blot of Nanos3 in human brain tissue lysate with Nanos3 antibody at 2 ug/ml. Immunofluorescence of Nanos3 in Human Brain cells with Nanos3 antibody at 20 ug/ml. |
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說(shuō)明書 |
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數(shù)量 |
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