品牌 |
Leading Biology | 貨號 |
APG01121G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality A2M / Alpha-2-Macroglobulin Antibody.
|
||
分子量 |
163kDa
|
||
細(xì)胞定位 |
Antigen Cellular Localization:
Secreted.
|
||
宿主 |
Goat
|
||
種屬反應(yīng)性 |
Human
|
||
靶點 |
Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-goat serum as well as purified and partially purified a2-Macroglobulin human plasma.
|
||
通用名 |
CPAMD5
|
||
基因ID |
|||
UniProt ID |
|||
功能 |
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
|
||
總結(jié) |
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
|
||
儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
應(yīng)用 |
WB, IHC-P, E, IP
|
||
稀釋方法 |
ELISA (1:40000-1:200000), IHC-P (3.75 μg/ml),
|
||
圖像 |
Anti-A2M / Alpha-2-Macroglobulin antibody IHC of human placenta. Anti-A2M / Alpha-2-Macroglobulin antibody IHC of human prostate. |
||
說明書 |
|||
數(shù)量 |
|
選擇 | 品牌 | 貨號 | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說明書 | 數(shù)量 | 目錄價 | |
1 | Leading Biology | APR05963G | EGFR Antibody (Y1092) | 100 μl | Polyclonal Antibodies |
|
¥4950.00 | 訂購 詢價 | ||
2 | Leading Biology | APR03116G | BRCA1 Antibody (aa1847-1863) | 100 μl | Polyclonal Antibodies |
|
¥4950.00 | 訂購 詢價 | ||
3 | Leading Biology | AMM05633G | Bombesin Receptor 2 (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
¥6950.00 | 訂購 詢價 | ||
4 | Leading Biology | APR10986G | AP3B1 Antibody (aa2-14) | 50 μg | Polyclonal Antibodies |
|
¥4950.00 | 訂購 詢價 | ||
5 | Leading Biology | APR11512G | Bestrophin-1 (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
¥6950.00 | 訂購 詢價 | ||
6 | Leading Biology | APG01407G | A3 Adenosine Receptor Antibody | 50 μl | Polyclonal Antibodies |
|
¥6950.00 | 訂購 詢價 |
微信掃描二維碼,隨時隨地與小諾親密接觸,精彩活動,勁爆優(yōu)惠,觸手可得!