品牌 |
Leading Biology | 貨號 |
APR02684G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FKTN / Fukutin Antibody.
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分子量 |
54kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
Human Fukutin. Predicted cross-reactivity based on amino acid sequence homology: mouse (90%), rat (91%).
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通用名 |
FCMD
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基因ID |
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UniProt ID |
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功能 |
Glycosyltransferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine- beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes. Could be involved in brain development.
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總結(jié) |
Glycosyltransferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine- beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes. Could be involved in brain development.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, ICC
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稀釋方法 |
ICC (1:100-1:200), IF (1:100-1:200), IHC-P (10 μg/ml), WB (1:500-1:3000) ,
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圖像 |
Immunofluorescence of methanol-fixed HeLa, using Fukutin antibody at 1:200 dilution. Sample (30 ug of whole cell lysate). Anti-FKTN / Fukutin antibody IHC of human skeletal muscle. |
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說明書 |
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數(shù)量 |
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