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當(dāng)前位置：首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > APC6 / CDC16 Antibody (N-Terminus)

APC6 / CDC16 Antibody (N-Terminus)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR02655G 50 μg / ￥4950

APC6 / CDC16 Antibody (N-Terminus)

品牌

 Leading Biology

貨號(hào)

 APR02655G

產(chǎn)品分類

 Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality APC6 / CDC16 Antibody (N-Terminus).

分子量
72kDa

細(xì)胞定位
Antigen Cellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Cytoplasm, cytoskeleton, spindle Note=Colocalizes with CDC27 to the centrosome at all stages of the cell cycle and to the mitotic spindle

宿主
Rabbit

種屬反應(yīng)性
Human, Mouse

靶點(diǎn)
Human CDC16

通用名
ANAPC6

基因ID

UniProt ID

功能
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

總結(jié)
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

儲(chǔ)存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用
WB, IHC-P, IF, E

稀釋方法
IHC-P (5 μg/ml), WB (1-2 μg/ml),

圖像

Immunofluorescence of APC6 in human liver tissue with APC6 antibody at 20 ug/ml.

Western blot of APC6 in human liver tissue lysate with APC6 antibody at (A) 1 and (B) 2 ug/ml.

Anti-CDC16 / Apc6 antibody IHC of human liver.

說(shuō)明書

數(shù)量

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