品牌 |
Leading Biology | 貨號 |
APG01113G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CD32B Antibody (C-Terminus).
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分子量 |
34kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein
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宿主 |
Goat
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
Human FCGR2B / CD32B. This antibody is expected to recognise all reported isoforms (NP_001002273.1; NP_001002274.1; NP_001002275.1; NP_003992.3; NP_001177757.1).
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通用名 |
CD32, FCG2, IGFR2
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基因ID |
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UniProt ID |
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功能 |
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
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總結(jié) |
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
ELISA (1:16000), IHC-P (3.75 μg/ml), WB (0.3-1 μg/ml)
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圖像 |
Antibody (0.3 ug/ml) staining of K562 lysate (35 ug protein in RIPA buffer). Anti-CD32B antibody IHC of human liver. |
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說明書 |
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數(shù)量 |
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