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當(dāng)前位置：首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > CD95 / FAS Antibody (Internal)

CD95 / FAS Antibody (Internal)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢(xún)價(jià)
APG01108G 50 μg / ￥4950

CD95 / FAS Antibody (Internal)

品牌

 Leading Biology

貨號(hào)

 APG01108G

產(chǎn)品分類(lèi)

 Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD95 / FAS Antibody (Internal).

分子量
38kDa

細(xì)胞定位
Antigen Cellular Localization: Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Secreted. Isoform 5: Secreted.

宿主
Goat

種屬反應(yīng)性
Human

靶點(diǎn)
Human FAS / CD95. This antibody is expected to recognize reported isoforms 1 (NP_000034.1), 2 (NP_690610.1) and 3 (NP_690611.1).

通用名
APT1, FAS1, TNFRSF6

基因ID

UniProt ID

功能
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

總結(jié)
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

儲(chǔ)存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用
WB, IHC-P, E

稀釋方法
ELISA (1:32000), IHC-P (3.75 μg/ml), WB (0.1-0.3 μg/ml)

圖像

FAS antibody (0.1 ug/ml) staining of MOLT4 lysate (35 ug protein in RIPA buffer).

說(shuō)明書(shū)

數(shù)量

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