品牌 |
Leading Biology |
貨號 |
APG01036G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HEC1 / NDC80 Antibody (C-Terminus).
|
分子量 |
74kDa
|
細胞定位 |
Antigen Cellular Localization:
Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore
|
宿主 |
Goat
|
種屬反應性 |
Human
|
靶點 |
Human NDC80 / HEC1.
|
通用名 |
HEC, HEC1, KNTC2
|
基因ID |
|
UniProt ID |
|
功能 |
Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
|
總結(jié) |
Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
|
儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
應用 |
WB, IHC-P, E
|
稀釋方法 |
ELISA (1:32000), IHC-P (5 μg/ml), WB (0.5-2 μg/ml)
|
圖像 |
Antibody staining (0.5 ug/ml) of HeLa lysate (RIPA buffer, 35 ug total protein per lane).
Anti-NDC80 / HEC1 antibody IHC of human adrenal.
Anti-NDC80 / HEC1 antibody IHC of human liver.
|
說明書 |
|
數(shù)量 |
|