品牌 |
Leading Biology | 貨號 |
APR02448G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TIRAP Antibody (N-Terminus).
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分子量 |
24kDa
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm. Cell membrane. Membrane. Note=Colocalizes with DAB2IP at the plasma membrane
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宿主 |
Rabbit
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種屬反應性 |
Human
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靶點 |
synthetic peptide corresponding to N-terminal residues of human TIRP(Toll/interleukin-1 receptor domain-containing adapter protein)
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通用名 |
MAL
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基因ID |
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UniProt ID |
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功能 |
Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.
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總結 |
Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, E
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稀釋方法 |
ELISA (1 μg/ml), IHC-P (10 μg/ml), WB (1 μg/ml)
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圖像 |
Anti-TIRAP antibody IHC of human skeletal muscle. |
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說明書 |
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數(shù)量 |
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