品牌 |
Leading Biology | 貨號 |
APR02105G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality USP4 Antibody (Internal).
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分子量 |
109kDa
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus Note=Shuttles between the nucleus and cytoplasm. Exported to the cytoplasm in a CRM1-dependent manner and recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor The relative amounts found in the nucleus and cytoplasm vary according to the cell type.
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宿主 |
Rabbit
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種屬反應性 |
Human, Rabbit, Monkey, Pig, Bovine, Dog
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靶點 |
Human USP4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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通用名 |
UNP, UNPH
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基因ID |
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UniProt ID |
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功能 |
Hydrolase that deubiquitinates target proteins such as the receptor ADORA2A, PDPK1 and TRIM21. Deubiquitination of ADORA2A increases the amount of functional receptor at the cell surface. May regulate mRNA splicing through deubiquitination of the U4 spliceosomal protein PRPF3. This may prevent its recognition by the U5 component PRPF8 thereby destabilizing interactions within the U4/U6.U5 snRNP. May also play a role in the regulation of quality control in the ER.
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總結 |
Hydrolase that deubiquitinates target proteins such as the receptor ADORA2A, PDPK1 and TRIM21. Deubiquitination of ADORA2A increases the amount of functional receptor at the cell surface. May regulate mRNA splicing through deubiquitination of the U4 spliceosomal protein PRPF3. This may prevent its recognition by the U5 component PRPF8 thereby destabilizing interactions within the U4/U6.U5 snRNP. May also play a role in the regulation of quality control in the ER.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
IHC-P
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稀釋方法 |
IHC-P (5 μg/ml)
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圖像 |
Anti-USP4 antibody APR02105G IHC of human thymus. |
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說明書 |
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數(shù)量 |
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