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ITGA3 / CD49c Antibody (N-Terminus)

APR02077G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR02077G		50 μg / ￥4950

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ITGA3 / CD49c Antibody (N-Terminus)

品牌	Leading Biology	貨號	APR02077G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ITGA3 / CD49c Antibody (N-Terminus).
分子量	117kDa
細胞定位	Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid-anchor. Cell projection, invadopodium membrane; Single-pass type I membrane protein. Cell projection, filopodium membrane; Single-pass type I membrane protein. Note=Enriched preferentially at invadopodia, cell membrane protrusions that correspond to sites of cell invasion, in a collagen-dependent manner
宿主	Rabbit
種屬反應性	Human, Bovine
靶點	Human ITGA3 / CD49c. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
通用名	MSK18
基因ID	3675
UniProt ID	P26006
功能	Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha- 3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
總結	Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha- 3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
形式	Liquid
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	IHC-P
稀釋方法	IHC-P (7.5-10 μg/ml)
圖像	Anti-ITGA3 / CD49c antibody APR02077G IHC of human skin.
說明書	Product Datasheet Protocol
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